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Senior Scientist (f/m/d) Process Development pDNA Downstream Processing Primary Recovery
Tübingen bei Stuttgart
Aktualität: 25.03.2023


25.03.2023, CureVac SE
Tübingen bei Stuttgart
Senior Scientist (f/m/d) Process Development pDNA Downstream Processing Primary Recovery
Scientific and disciplinary management of a team responsible for the development, optimization and upscaling of GMP-compliant manufacturing processes for nucleic acids with focus on plasmid DNA Planning, execution, interpretation and documentation of experiments Perform small-scale validation and process characterization studies Support transfer of production steps to routine production Preparation of development reports, technical documents, risk analyses, laboratory instructions, training documents and SOPs Subject Matter Expert (SME) for process development topics at C(D)MOs as well as technology transfers to GMP production sites Participation in multidisciplinary project teams Supervision of external development activities
PhD in Biotechnology, Biochemical Engineering or related field Extensive professional experience in process development of scalable and efficient biopharmaceutical purification processes, ideally in pharmaceutical/ biotech industry or relevant PostDoc experience Relevant professional experience in the production of biopharmaceuticals and process characterization Hands-on experience in primary recovery (cell lysis, cell debris clarification, precipitation and filtrations) Profound knowledge in developing scalable, cost-effective biopharmaceutical production processes Good theoretical and practical knowledge in molecular biology and bioanalytics Experienced in design of experiments (DoE) Ability to independently devise research projects but also to work in an interdisciplinary team Strong communication skills and team-oriented work style Fluency in German and English