Characterization of primary tumors on different molecular levels using state-of-the-art methods (e.g. genomics, transcriptomics, metabolomics) Application and adaption of a broad spectrum of molecular and cell biological techniques, including FACS analyses, immunohistochemistry, and immunofluorescence Establishment and characterization of patient-derived tumor models (e.g., organoids) Functional testing of drug effects using in vitro and pre-clinically relevant in vivo models Analysis of clinical and experimental datasets (e.g., immunohistochemistry, gene expression) using established biostatistics and bioinformatics approaches A close link to clinical aspects of cancer research as primary research aim