PhD Student (all gender), Translational Pediatric Oncology Research - Clinic for Pediatric and Adolescent Medicine
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Frankfurt am Main
Informationen zur Anzeige:
PhD Student (all gender), Translational Pediatric Oncology Research - Clinic for Pediatric and Adolescent Medicine
Frankfurt am Main
Aktualität: 28.11.2025
Anzeigeninhalt:
28.11.2025, Universitätsklinikum Frankfurt
Frankfurt am Main
PhD Student (all gender), Translational Pediatric Oncology Research - Clinic for Pediatric and Adolescent Medicine
Aufgaben:
The successful candidate will become part of an interdisciplinary and collaborative team committed to translating molecular insights into new precision-oncology strategies for children with cancer.
Design and perform CRISPR-based genetic perturbation screens in patient-derived and engineered cancer models
Analyze and interpret epigenetic, transcriptomic, and proteomic datasets using state-of-the-art statistical and computational approaches
Functionally validate candidate genes, pathways, and molecular mechanisms in cellular model systems
Contribute to the development and preclinical evaluation of targeted therapeutic strategies for high-risk pediatric tumors
Present results within the research group and at scientific meetings, and contribute to publications
Collaborate closely with clinicians, molecular biologists, and computational scientists within an interdisciplinary environment
Qualifikationen:
Master's degree in Life Sciences or a related discipline
Strong interest in uncovering novel therapeutic strategies and in understanding epigenetic and transcriptional mechanisms of gene regulation
Practical experience with standard molecular biology techniques (e.g., cloning, PCR, flow cytometry)
Basic proficiency in bioinformatics and experience analyzing high-throughput datasets (e.g., RNA-seq, proteomics)
Motivation to work independently as well as collaboratively within an interdisciplinary research team
Excellent communication skills and proficiency in written and spoken English
Due to legal regulations, valid proof of measles immunity / measles vaccination is required.
Berufsfeld
Öffentlicher Dienst, Verwaltung
Forschung, Lehre
Forschung & Entwicklung
Pharma, Chemie, Med., Biotechn.
Biologische, Klinische F&E
Labor
Bundesland
Standorte
